ALEX 3 IgE - Allergen Screening of 300 allergens

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

ALEX 3 (Allergy Xplorer) is a multiplex allergy test designed for the simultaneous evaluation of specific IgE (sIgE) and total IgE (tIgE) across an extended panel of 300 allergens.

The test includes allergens selected from sources with high clinical relevance, such as animal epithelia, house dust mites, molds, pollens, cereals, egg, legumes, milk, seafood, tree nuts, and insect venoms.

The test comprises 218 molecular allergens and 82 allergen extracts, including 107 unique molecular components, providing a comprehensive and precise profile of allergic sensitization.

The combination of allergen extracts and molecular allergens allows for a clearer and more comprehensive characterization of sensitization, as these two components complement each other in the patient’s evaluation. The molecular component adds greater precision to result interpretation, facilitating the differentiation between clinically significant sensitizations and those with lower clinical relevance, including cases within the same allergen source.

Thus, the test provides valuable information for assessing clinical risk, clarifying cross-reactivity, and guiding medical management.

Indications

• symptoms of allergic reactions: runny nose, nasal congestion, sneezing, watery eyes
• skin manifestations: itching, skin rashes, urticaria, dermatitis
• cough, difficulty breathing, suspected allergic rhinitis or bronchial asthma
• suspected food or inhalant allergy
• need to identify triggers of allergic reactions
• comprehensive diagnosis of allergic conditions in children and adults

Procedure

• For the analysis, a small amount of venous blood is collected. The procedure is performed by a medical professional in a laboratory setting, in accordance with all safety standards, and takes only a few minutes.
• After collection, the blood sample is sent to a specialized laboratory for further investigation using modern diagnostic technologies.
• In the laboratory, a multiplex analysis is performed, allowing the simultaneous determination of specific IgE antibodies (sIgE) to a large number of allergens included in the test panel, as well as the total IgE level (tIgE).
• The high sensitivity of the method allows the detection of even low levels of sensitization to allergens and provides a detailed profile of the patient’s allergic sensitivity.
• The obtained results help the physician identify possible allergy triggers, assess clinical risks, clarify potential cross-reactivity, and determine the most appropriate treatment or prevention strategy.
• Blood collection is generally well tolerated by patients and does not require special preparation. After the procedure, the patient can immediately return to their normal daily activities.

Sources:

https://www.alpco.com/resources/understanding-ige-allergy-test-results
https://onlinelibrary.wiley.com/doi/full/10.1111/cea.14350
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156228/
https://www.madx.com/extras

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or worsening of symptoms, it is essential to consult a healthcare professional for proper diagnosis and treatment. Only a qualified specialist can accurately diagnose and determine the appropriate course of action. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.